OMG noooo! There went my plans to pre-foul the bore of my Krag before shooting in the Vintage match next week! I was going to use a load with a different powder and bullet from what I'll be shooting in the match! No really, I think the effects of different powder residue would be minimal, unless you're shooting something like 860 which leaves a lot of residue, before shooting your pet load. Maybe if we were talking about benchrest shooting one could find a bit of an effect.
"I have sworn upon the Altar of God, eternity hostility upon all forms of tyranny over the minds of man." - Thomas Jefferson