In 30 years as a cop, mostly spent in Patrol, I never found a comfortable ankle holster. Ended up as follows: Carried a .380 (hollowpoints) in a shoulder rig, that I put on after I put on my protective vest. It was snugged down on my left side and I could reach it easily if needed. "If needed", meant that the situation was close up and personal, and popping off a shirt button wasn't a consideration at the moment.
Only folks I ever saw comfortable with an ankle holster were Detectives sitting at their desks.
"No man's life, liberty, or property is safe, while Congress is in session." Mark Twain